Biochemistry (M.Sc.)

These pages are not displaying properly because the Compatibility View in your Internet Explorer is enabled. We suggest that you remove 'fu-berlin.de' from your list of sites that have Compatibility View enabled.

  1. In Internet Explorer, press the 'Alt' key to display the Menu bar, or press and hold the address bar and select 'Menu bar'.
  2. Click 'Tools' and select 'Compatibility View settings'.
  3. Select 'fu-berlin.de' under 'Websites you've added to Compatibility View'.
  4. Click 'Remove'.

Shaping Cells and Tissues

Morphogenesis, i.e. the process of shaping biological structures, requires a plethora of interconnected processes. Signaling gradients and mechanical forces, to name a few, constantly instruct cells to migrate, proliferate, differentiate and change their polarity etc. Elucidating these principles paves the way towards understanding the formation of complex three-dimensional structures with prospective utilization in biomedical research of embryonic development and regenerative approaches.

  • What are the signaling principles that allow the formation of elaborate 3D structures such as the vertebrate limbs? What are the key regulators?
  • Cells attach to extracellular macromolecular structures, the extracellular matrix. Which transmembrane receptors are mainly used for this purpose? How do cells achieve a mechanical coupling between the extracellular matrix and the cytoskeleton? How could this influence gene transcription?
  • What defines a stem cell, what is a stem cell niche? Based on this, which mechanisms are active in stem cells as opposed to other somatic cells allowing them to fulfill their functions?
  • Name and explain the basic principles of techniques that could be used to analyze expression patterns in development.
  • Cellular functions rely on gene expression. Which methods can be used to analyze the expression of a specific gene of interest and genome-wide gene expression in vitro? How can you proceed in a specific cell type in its tissue context (piece of tissue, tissue section)?